Prednisone is an oral, synthetic corticosteroid drug that is used as an immunosuppressant and to treat certain inflammatory diseases. Similar to other corticosteroids, prednisone mimics the effects of hormones secreted from the adrenal glands, suppressing inflammation and allergic-type reactions.

Prednisone can be used at varying doses in patients diagnosed with myelofibrosis (MF) or anemia. Prednisone can be used to improve symptoms, stimulate appetite, improve blood counts. With the introduction of JAK2 inhibitors (ruxolitinib), prednisone use is less and less common. Discuss with your physician to determine if this is right for you.

Side Effects

Common side effects:

  • Nausea and/or vomiting
  • Loss of appetite
  • Weight gain
  • Heartburn
  • Trouble with sleeping
  • Upset stomach or stomach irritation
  • Increased sweating
  • Mental or mood changes

Additional Information:

Richard T. Silver MD Myeloproliferative Neoplasms Center 525 East 70th St., Starr Pavillion, 3rd Floor New York, NY 10021