Pregnancy and MPNs

Pregnant woman with hands on her stomach.

With appropriate management, most pregnant patients with MPNs deliver healthy babies. However, expectant mothers with MPNs may be at increased risks of miscarriage or other complications. These risks can be higher in patients with a prior history of pregnancy complications, blood clots, and/or bleeding associated with their MPN. Pregnant patients require more frequent monitoring and may require therapy to minimize risk of complications. 

Treatment Overview

Coordinated care between obstetricians and hematologist-oncologists is important during pregnancy for expectant mothers with MPNs. Care is individualized based upon patient risks of thrombosis. Clinicians at the Silver MPN Center and Obstetricians at Weill Cornell Medicine have cared for many pregnant women with MPNs.

Related Faculty

Stephen T. Chasen, M.D., FACOG

Stephen T. Chasen, MD, FACOG

Stephen T. Chasen, M.D., FACOG

Maria DeSancho, M.D.

Dr. Maria DeSancho is an Associate Professor of Medicine in the Division of Hematology and Medical Oncology at Weill Cornell Medicine. She received her medical degree from the Autonomous University in Spain and completed residencies at the La Paz Hospital in Spain and the Metropolitan Hospital Center in New York, with fellowships in hematology at Montefiore Medical Center and the Mount Sinai Medical Center, including advanced training in transfusion medicine and bone marrow transplantation. Prior to joining the Weill Cornell faculty in 2006, she was Assistant Clinical Professor at Columbia University and Assistant Attending Physician at the Mount Sinai Medical Center in New York.

Dr. DeSancho serves as Chief of the Non-Malignant Hematology Service. Dr. DeSancho has a special interest in bleeding and thrombotic disorders including in the myeloproliferative neoplasms (MPNs), particularly in pregnant and postpartum women. Dr. DeSancho diagnoses, treats and follows patients with myeloproliferative neoplasms. Additionally, Dr. DeSancho participates in a bi-monthly myeloproliferative neoplasms conference run by the Hematology and Medical Oncology Division in conjunction with the Pathology Department, as part of NewYork-Presbyterian and Weill Cornell Medicine’s commitment to offer MPN patients the best possible treatment using a multidisciplinary approach. 

Clinical Profile (POPS)
Maria DeSancho, M.D.

Maria DeSancho, M.D.

Robin B. Kalish, M.D., FACOG

Robin B. Kalish, M.D., FACOG

Robin B. Kalish, M.D., FACOG

Richard T. Silver MD Myeloproliferative Neoplasms Center 525 East 70th St., Starr Pavillion, 3rd Floor New York, NY 10021 SilverMPNCenter@med.cornell.edu