Title | Essential thrombocythemia in a child with elevated thrombopoietin concentrations and skeletal anomalies. |
Publication Type | Journal Article |
Year of Publication | 2008 |
Authors | Robins EB, Niazi M |
Journal | Pediatr Blood Cancer |
Volume | 50 |
Issue | 4 |
Pagination | 859-61 |
Date Published | 2008 Apr |
ISSN | 1545-5017 |
Keywords | Aspirin, Bone and Bones, Child, Preschool, Enzyme Inhibitors, Female, Humans, Hydroxyurea, Male, Mothers, Pedigree, Platelet Count, Thrombocythemia, Essential, Thrombopoietin |
Abstract | Essential thrombocythemia is a rare myleoproliferative disorder in pediatrics. This myeloproliferative disorder is characterized by excessive proliferation of megakaryocytes and sustained elevation of platelet count. Reactive thrombocytosis is a more common cause of elevated platelet counts among children. We describe a 2-year-old child with essential thrombocythemia, skeletal anomalies, and elevated thrombopoietin concentrations. The child's mother was also subsequently diagnosed with essential thrombocythemia and had elevated thrombopoietin concentrations. Chromosomal studies on the mother, child and other family members were normal. |
DOI | 10.1002/pbc.21218 |
Alternate Journal | Pediatr Blood Cancer |
PubMed ID | 17455310 |
Submitted by job2075 on July 14, 2017 - 3:56pm